The US vetoed a UN Security Council demand for an immediate ceasefire in Gaza, even as it kept up pressure on Israel to do more to protect Palestinian civilians during a fierce offensive against Hamas militants across the enclave.
Fighting escalated and the Palestinian death toll rose on Saturday, with Israel pounding the enclave from north to south in an expanded phase of the two-month-old war against the Iran-backed Islamist group Hamas.
Decrying a "spiralling humanitarian nightmare", UN Secretary-General Antonio Guterres on Friday declared that nowhere in Gaza was safe for civilians, hours before the U.S. vetoed a Security Council resolution backed by the vast majority of its members calling for a humanitarian ceasefire in Gaza.
The vote left Washington diplomatically isolated on the 15-member council. Thirteen members voted in favor of the draft resolution put forward by the United Arab Emirates, while Britain abstained.
Deputy U.S. Ambassador to the U.N. Robert Wood told the council: "We do not support this resolution's call for an unsustainable ceasefire that will only plant the seeds for the next war."
The United States and Israel oppose a ceasefire, saying it would benefit Hamas, which Israel has vowed to annihilate in response to the militants' deadly October 7 cross-border rampage.
Washington instead supports "pauses" like the seven-day halt in fighting that saw Hamas release some hostages and the humanitarian aid flow increase. The deal broke down on December 1.
Palestinian U.N. envoy Riyad Mansour told the council the vote means that "millions of Palestinian lives hang in the balance."
Ezzat El-Reshiq, a member of Hamas' political bureau, condemned the US veto as "inhumane."
Israel's U.N. Ambassador Gilad Erdan said in a statement: "A ceasefire will be possible only with the return of all the hostages and the destruction of Hamas."
In Iran, the main backer of Hamas, foreign ministry spokesperson Nasser Kanaani said: "Once again the U.S. government has demonstrated that it is the main actor in the killing of Palestinian civilians, particularly women and children, and the destruction of Gaza's vital infrastructure."
The White House on Friday said more could be done by Israel to reduce civilian casualties and the U.S. shared international concerns about the humanitarian situation in Gaza.
"We certainly all recognize more can be done to try to reduce civilian casualties," White House national security council spokesman John Kirby told reporters.
On Thursday, U.S. Secretary of State Antony Blinken sharpened Washington's language, saying it was imperative that Israel took steps to safeguard Gaza's civilian population. "And there does remain a gap between...the intent to protect civilians and the actual results that we're seeing on the ground," he told a press conference.
Describing the situation as "at a breaking point," Guterres said the collapse of Gaza's humanitarian system could result in a complete breakdown of public order. Most Gazans are now displaced, hospitals overrun and food running out.
Residents and the Israeli military both reported intensified fighting in both northern areas, where Israel had previously said its troops had largely completed their tasks last month, and in the south where they mounted a new assault this week.
Gaza's health ministry on Friday said the death toll from Israel's campaign in Gaza had risen to 17,487. Early on Saturday it said another 71 dead and 160 injured people had arrived at Al Aqsa hospital in the past 24 hours.
More strikes were reported on Friday in Khan Younis in the south, the Nusseirat camp in the centre and Gaza City in the north. On Friday evening, residents reported intensified Israeli tank fire in north Gaza, while health officials said at least 10 people were killed in an air strike on a house in Khan Younis.
Israel's military said 94 Israeli soldiers had been killed fighting in Gaza since its ground invasion of the densely populated enclave began in mid-October in retaliation for Hamas' rampage in southern Israel in which militants killed 1,200 people and took more than 240 hostages.